Opposing glycemic response Vs prebiotic fibre in daily staples?

Food as medicine is one thing but pizza as medicine is another thing altogether. The most addictive, popular junk food! a vehicle for health transformation? Tell me more.

We have a range of flour and sugar substitutes that can be used to seamlessly modify the glycemic response relative to the prebiotic properties of every day favorite foods. Compliance issues for dietary changes is always a concern. So, accomplishing all these things with, for example your favorite pizza is a win-win, no?

Why you might recommend controlling carb to fibre ratio

Carb Cycling

· Train low, compete high?

· reduce body fat to improve strength to weight ratio,

· improve mitochondrial function,

· increase metabolic flexibility and

· endurance through fat adaption

· while providing carbs at appropriate times before competition.

Adverse effects of spiking blood glucose and insulin levels

· Increased fat storage and hunger

· Inflammatory signaling

· Suppression of autophagy which involves recycling damaged proteins & muscle repair.

· Suppression of macrophage phagocytic activity which involves recycling 4 million dead cells every second!

· Glucose toxicity from high postprandial blood glucose

· Suppression of mitochondrial function and mitophagy.

Prebiotic Fibre?

· Gut function is critically dependent on microbial metabolites from fibre fermentation

· The Role of the Gut in Everything, from fatigue, motivation, energy levels, injury recovery, immunity, resistance to infection, etc., etc.

· It is mind boggling to realize that the gut lining has the surface area of a tennis court. The colonic epithelial cells live for just 3 days and 10 billion cells must be generated every day. The energy for this prodigious task comes from short chain fatty acids produced bacterial breakdown of fibre.

· Permeability barrier is dependent on the short chain fatty acid butyrate.

· Gut strength and function dependent on butyrate

· Elite athletic performance is stressful on gut function

· Endurance is enhanced by availability of SCFA

· SCFA receptors present on muscle cells

· SCFA regulates GLP1 secretion with widespread effects on metabolism & ↓appetite

· SCFA and exercise--review

· SCFA in Immune regulation

· SCFA in gut barrier function related inflammation, sickness behaviour and fatigue

· Gut muscle axis

· Does the intestinal microbiome affect athletic performance?

· Cytokine induced sickness behavior

· Drastic Effects on the Microbiome of a Young Rower Engaged in High-Endurance Exercise After a Month Usage of a Dietary Fiber Supplement

· No guts no glory-infographic